Five-lipoxygenase products in asthma

Sven-Erik Dahlen, T. H. Lee

A critical reference for every asthma researcher and clinician, Five-Lipoxygenase Products in Asthma highlights agents and products of the 5-LO pathway and its relationship to other pathways ... explores the enzymology of the 5-LO pathway with focus on leukotriene transport, degradation, and excretion ... details the role of protein identification in the 5-LO pathway ... describes human cell types that produce leukotrienes and their activation ... outlines pharmacological and binding study evidence for leukotriene receptors ... discusses the recovery of leukotrienes in lung disease ... analyzes leukotriene receptor antagonists and synthesis inhibitors by specific agent ... provides a "by entity" summary of individual drug information in exercise-induced, allergen-induced, aspirin-induced, and chronic stable asthma ... profiles the use of agents active on the 5-LO pathway in asthma...