Aspirin myocardial infarction study, 1975-1979

United States. Department of Health and Human Services, National Heart, Lung, and Blood Institute, Inter-university Consortium for Political and Social Research

The Aspirin Myocardial Infarction Study was conducted to determine whether the daily administration of at least one gram of aspirin to persons who had at least one documented myocardial infarction would result in a significant reduction in total mortality over a three year period. Secondary objectives were to evaluate the effects of aspirin in this group on the incidence of coronary heart disease mortality, coronary incidence, fatal or nonfatal strokes, and intermittent cerebral ischemic attacks. Other objectives were to evaluate side or adverse effects of long-term aspirin therapy, to study the natural history of coronary heart disease by following patients in a placebo group, and to advance the methodology of long-term cooperative clinical trials. Initial Visit Form variables include age, sex, race, birthdate, lifestyle, work status, and marital status, as well as thorough physical...